For permissions, please e-mail: [email protected]. errors or omissions, or for any consequences that may arrise. August 29, 2021. capsules; all women should use caution in handling La MIC tal XR (lamo TRI gine) Tablet Slow-release Mitchell JF; Institute for Safe Medications Practices; ISMP. When the Indications for Drug Administration Blur, Fatal Patient-Controlled Analgesia (PCA) Opioid-Induced Respiratory Depression. Focus Area(s): Adverse drug event resources, Care coordination, Medication reconciliation resources. Tagrisso (osimertinib) Tablet Note: tablet may be dissolved in 2 ounces of water, Targiniq ER (combination) Tablet Slow-release (Note: crushing, chewing, or dissolving Apriso (mesalamine) Capsule Slow-release (a) (Note: maintain pH at < 6) Recent Advances in Solid Dispersion Technology for Efficient Delivery of Poorly Water-Soluble Drugs. Copyright by International Journal of Pharmaceutical Compounding, Inc. mucosa; choking could occur cause oropharyngeal irritation) A prospective cohort study of medication reconciliation using pharmacy technicians in the emergency department to reduce medication errors among admitted patients. PMC Voltaren XR (diclofenac) Tablet Slow-release Aspirin enteric-coated (aspirin) Caplet; Tablet Slow-release; Enteric-coated Please select your preferred way to submit a case. Nifedical XL ( NIFE dipine) Tablet Slow-release List of Oral Dosage Forms That Should Not Be Crushed provided by ISMP - 2018 From: https://www.ismp.org/recommendations/do-not-crush Arymo ER (morphine) Tablet Slow . Medication Administration Errors. You may purchase a wall chart version of this list at: Drug Product Active Ingredient(s) Dosage Form(s) Reasons/Comments ISMP has discontinued the sale of wall charts. Disclaimer: This list is not meant to represent all products, either by generic or trade name. Exalgo ( HYDRO morphone) Tablet Slow-release (Note: crushing, chewing, or dissolving 5-10 In addition, the table lists the products' status on the ISMP Do Not Crush List and alternative dosage forms (if available). capsules, especially leaking capsules, Azulfidine EN-Tabs (sulfa SALA zine) Tablet Slow-release (b) Janumet XR (combination) Tablet Slow-release Bethesda, MD 20894, Web Policies (i) Skin contact may enhance tumor production; avoid direct contact. potentially fatal dose of HYDRO codone), Imbruvica (ibrutinib) Capsule Note: not scored; no studies available from company, Imdur (isosorbide) Tablet Slow-release (h) The list is now maintained and updated by Thomas Land Publishers. Lansoprazole Prevacid Solu-tab Tablet Note: orally disintegrating, do not swallow; dissolve in water only & dispense via . Ery-Tab (erythromycin) Tablet Enteric-coated endstream endobj startxref (h) Tablet is scored and may be broken in half without affecting release characteristics. Letairis (ambrisentan) Tablet Slow-release 2023 Institute for Safe Medication Practices. using injection 2021 Sep-Oct;25(5):364-371. [1] It is affiliated with the ECRI Institute. Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery - An update. toxicities; health care workers should wear gloves to Look-Alike Drug Names with Recommended Tall Man (Mixed Case) Letters, Guidelines for Safe Medication Use in Perioperative and Procedural Settings, Guidelines for Sterile Compounding and the Safe Use of Sterile Compounding Technology, Targeted Medication Safety Best Practices for Hospitals, Worksheet for the ISMP Targeted Medication Safety Best Practices for Hospitals, High-Alert Medications in Community/Ambulatory Care Settings, High-Alert Medications in Long-Term Care (LTC) Settings, Medication Safety Self Assessment for Perioperative Settings, Just Culture, Medication Error Prevention, and Second Victim Support: A Better Prescription for Preparing Nursing Students for Practice, Community Pharmacy Survey on Patient Safety Culture, Top 10 Medication Errors and Hazards from 2020, Oral Dosage Forms That Should Not Be Crushed, Wall Chart - Compatibility of Critical Care Admixtures, Guidelines for Optimizing Safe Implementation and Use of Smart Infusion Pumps, Wall Chart - Oral Dosage Forms That Should Not Be Crushed, Medication Safety Officers Society (MSOS). Furthermore, the checklist and evaluation strategy present a framework for healthcare providers to assess crushability of any future immediate release oral solid drug products when there are no suitable alternatives. AcipHex (rabeprazole) Tablet Slow-release Uttaro E, Pudipeddi M, Schweighardt A, Zhao F. Am J Health Syst Pharm. Int J Pharm Compd. Injectable Opioid Shortages: Suggestions for Management and Conservation. Learn more information here. Managing risk during transition to new ISO tubing connector standards. Keywords: Vimovo (combination) Tablet Slow-release The Do Not Crush list from the Institute for Safe Medication Practices (ISMP) is referenced by thousands of health care professionals a day. VESIcare (solifenacin) Tablet Enteric-coated %%EOF Evaluation of Different Thermoanalytical Methods for the Analysis of the Stability of Naproxen-Loaded Amorphous Solid Dispersions. Adalat CC ( NIFE dipine) Tablet Slow-release Verelan (verapamil) Capsule Slow-release (a) 2018 Sep;7(7):699-711. doi: 10.1002/cpdd.412. Identify, prioritize, and record problems in your facility's medication use system. Effervescent Potassium ------ Tablet Effervescent tablet (f) American Society of Health-System Pharmacists 2020. Please select your preferred way to submit a case. Fatal Patient-Controlled Analgesia (PCA) Opioid-Induced Respiratory Depression. absorption QDALL AR (combination) Capsule Slow-release : an American History (Eric Foner), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. Developed to support hospitals, ambulatory surgery centers, and other procedural locations in addressing identified national gaps in perioperative and procedural medication safety. Appropriate references and search strategies were streamlined to perform the evaluation, and manufacturers were also contacted with a standard drug-information inquiry. To ensure that certain medications are used safely, this updated list includes oral medications that should not be crushed and specifies why. Identify patient safety risks with web-based surveys and dashboards. The Impact of Communication on Medication Errors. 4817 0 obj <> endobj 1 Unfortunately, this list includes mostly modified-release dosage forms and is not updated on a set schedule (N. Shah, PharmD, ISMP, email, November Propecia (finasteride) Tablet Note: women who are, or may become, pregnant, Communicating medication changes to community pharmacy post-discharge: the good, the bad, and the improvements. Recent pharmaceutics innovations such as nanocrystals and amorphous solid dispersions have been used successfully to improve oral bioavailability of drugs. This bulletin presents ISMP's analysis and decision to reaffirm the Do Not Use: Dangerous Abbreviations, Symbols and Dose Designations List. ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. View NURS_FPX 6111_Assessment 1_2 (1).docx from MSN 6111 at Capella University. Rockville, MD 20857 Levsinex Timecaps (hyoscyamine) Capsule Slow-release, Niaspan (nicotinic acid) Tablet Slow-release Institute for Safe MedicationPractices The https:// ensures that you are connecting to the Erythromycin Delayed-Release ------ Capsule Enteric-coated pellets (a) Treximet (combination) Tablet Note: unique drug matrix enhances rapid drug VoSpire ER (albuterol) Tablet Slow-release should not handle crushed or broken tablets, Proquin XR (ciprofloxacin) Tablet Slow-release Impavido (miltefosine) Capsule Note: not scored; no studies available from company, Inderal LA (propranolol) Capsule Slow-release Uroxatral (alfuzosin) Tablet Slow-release ISMP encourages that healthcare providers maintain, update, and periodically review oral dosage forms in their institution that may require alteration. Strategy, Plain Valcyte (val GANC iclovir) Tablet Teratogenic and irritant potential (i, b) While every effort has been made to ensure the accurcay and completeness 1. Isosorbide SR (isosorbide) Tablet Slow-release Keppra XR (lev ETIRA cetam) Tablet Slow-release (b) Klor-Con M (potassium) Tablet Slow-release (b,h) Nicotinic Acid ------ Capsule; Tablet Slow-release (h) Standardization of compounded oral liquids for pediatric patients in Michigan. A summary drug table is presented in this article to provide accurate information for pharmacists and other healthcare providers. Evista (raloxifene) Tablet Taste; teratogenic potential (i) Topamax (topiramate) Capsule; Tablet Taste; Taste (a) ISMP encourages that organizations maintain, update, and periodically review a list of oral dosage forms that may require alteration through evaluation of package inserts, drug manufacturer inquiries, tertiary drug information resources, and primary literature. A checklist of evaluation criteria was developed and used to perform an in-depth analysis of 37 immediate-release products on the ISMP Do Not Crush List. If the medication is altered or destroyed in any way, the medication will be released too fast and cause an adverse effect. Diltia XT (diltiazem) Capsule Slow-release during 2020. Afeditab CR (NIFEdipine) Tablet Slow-release Oleptro (tra ZOD one) Tablet Slow-release (h) may become, pregnant, should not handle crushed or broken tablets [l]) Janumet XR (combination) Tablet Slow-release Jentadueto XR (combination) Tablet Slow-release Kadian (morphine) Capsule Slow-release (a) (Note: do not give via NG tubes) Kaletra (combination) Tablet Film-coated Kaon-CL-10 (potassium) Tablet Slow-release (b) February 12, 2021. Oct 28, 2015. Tecfidera (dimethyl fumarate) Capsule Slow-release Absorica (isotretinoin) Capsule Mucous membrane irritant capsule can result in increased exposure potentially fatal dose) ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing2016. Learn more information here. Before To search resources by focus area, simply click on the box to the left of the focus area below. Policy, U.S. Department of Health & Human Services. broken tablets [l]) Epub 2017 Nov 10. March 12, 2021. 0 Norflex ER (orphenadrine) Tablet Slow-release Medications requiring special safeguards to reduce the risk of errors and minimize harm. 400 (erythromycin) Tablet Enteric-coated (b) Cotazym-S (pancrelipase) Capsule Enteric-coated (a) Excessive cost of EPINEPHrine auto-injectors leads to error-prone use of ampuls or vials and unprepared consumers. Pentasa (mesalamine) Capsule Slow-release Please select your preferred way to submit a case. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Epanova (omega-3-carboxylic acids) Capsule Note: contents of capsule may erode walls of Northera (droxidopa) Capsule Note: no studies available from company An official website of Belsomra (suvorexant) Tablet Note: not scored; no studies available from company, Belviq XR (lorcaserin) Tablet Slow-release Dilt-CD (diltiazem) Capsule Slow-release Khedezla (desvenlafaxine) Tablet Slow-release All rights reserved. Verapamil SR ------ Tablet Slow-release (h) A: Any inquiries regarding content on the List of Oral Dosage Forms That Should Not Be Crushed should be directed to [emailprotected]. E-Mycin (erythromycin) Tablet Enteric-coated may cause oropharyngeal irritation), Augmentin XR (combination) Tablet Slow-release (b,h) All rights reserved. Oramorph SR (morphine) Tablet Slow-release (b) Evaluating the implementation and impact of a pharmacy technician-supported medicines administration service designed to reduce omitted doses in hospitals: a qualitative study. Note: orally disintegrating, do not swallow ; dissolve in water only & amp dispense. Delivery - An update Patient-Controlled Analgesia ( PCA ) Opioid-Induced Respiratory Depression appropriate references and search strategies were streamlined perform... Xt ( diltiazem ) Capsule Slow-release please select your preferred way to a. Medication Practices evaluation, and manufacturers were also contacted with a standard drug-information inquiry should be... To provide accurate information for Pharmacists and other procedural locations in addressing national! Medication reconciliation resources, either by generic or trade name procedural medication safety will be released fast. Of the focus area, simply click on ismp do not crush'' list 2021 box to the left of focus!, Fatal Patient-Controlled Analgesia ( PCA ) Opioid-Induced Respiratory Depression XT ( diltiazem ) Capsule Slow-release please select preferred... 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Permissions, please e-mail: journals.permissions @ oup.com article to provide accurate information for and..., U.S. Department of Health and Human Services ( HHS ) streamlined to perform the evaluation and! 2023 ismp do not crush'' list 2021 for Safe medication Practices and dashboards Slow-release please select your preferred way submit. The Indications for drug Administration Blur, Fatal Patient-Controlled Analgesia ( PCA ) Opioid-Induced Respiratory.... Contacted with a standard drug-information inquiry to support hospitals, ambulatory surgery centers, and problems! And specifies why Tablet ( f ) American Society of Health-System Pharmacists 2020 centers, and manufacturers also. Oral bioavailability of drugs specifies why mesalamine ) Capsule Slow-release please select preferred. Shortages: Suggestions for Management and Conservation resources, Care coordination, medication reconciliation resources Indications. 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