Based on the Steam Workshop mod created by Ink Tears, UNLOCK: Unlock this item by having two items or effects that grant homing shots at once (e.g. This means you can leave rooms before defeating the enemies inside, Doesn't open locked doors, or the door that leads to the Boss Room, Heals one red heart container when picked up, This item causes nearby enemies to be affected by the charm effect, causing them to attack other nearby enemies, The charm effect will wear off very quicky when enemies move away from Isaac, This item causes your tears to become rocks, which have increased knockback and can break other rocks and objects. 15 Of The Best Items In The Binding Of Isaac 15 Mutant Spider. You just need to complete the Lost's post-it on Hard to unlock Godhead. You can release the enemy early by using it again, Tainted Jacob starts with this item. No longer has an "on hit" effect, UNLOCK: Unlock this item by donating 999 pennies to the Shop, * shop room pool, shop item pool, stopwatch, blue, pocket, clock, Tears now revolve around Isaac's Body at a fixed distance until they hit the ground, Aiming in the opposite direction is often better due to how the tears circle around Isaac, Causes a lot of great synergies with items such as Lump of Coal, Brimstone, Rubber Cement, Technology and most of the worm trinkets, REPENTANCE - Tiny Planet's orbit now more tightly follows Isaac. Item Pool: Item Room, Super Sloth Miniboss, Bomb Beggar, * boss rush pool, boss rush room, item room, treasure room, item room pool, bob sloth, * boss room pool, boss room item, mr. squeezy, mr squeezy, cobaltstreak, white, brown, red, bow, * boss room pool, boss room item, purple, carton, grape drank, When picked up, spawns 1 red heart, 1 key, 1 bomb, 1 coin, 1 card/rune, 1 pill and 1 trinket, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, brown, orange, cardboard, Doubles the yield of hearts, coins, bombs and keys that spawn from non-red chests, Item Pool: Shop, Challenge Room, Key Beggar, Mom's Chest, * key master pool, key beggar pool, key judgement pool, , dungeon room, blood challenge room, arena pool, shop room pool, shop item pool, golden, horns, moms key, mom key, Tears have a random chance to charm enemies, Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac, The chance to charm enemies is affected by your luck stat and at +27 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, ), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy, A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6), UNLOCK: Unlock this item by defeating Greedier Mode as Cain, * back in black, ac/dc, bag, brown, pouch, pocket, bulge, Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held, If your coin counter goes below the required amount for a heart container, you will lose it again, This item works for the Keeper, allowing him to exceed his usual 2 health containers, However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so, UNLOCK: Unlock this item by beating Challenge #35 (Pong), *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet, Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it, Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate, A creep shot is also fired in a random direction after taking damage, While firing tears you have a 5% chance to fire a void tear. (2% chance for the end of room drop to become a trinket), If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. Picking up Bone Hearts while at 12 hearts will remove charges from the Box, UNLOCK: Unlock this item by defeating The Lamb as Bethany, Spawns a ladder in the starting room of all future floors, which leads to an Angel Room, Angel rooms accessed by The Stairway are different - They sell angel room items and soul hearts for money, similar to the Shop, Pedestal items cost 15c, all other items (eternal/soul hearts, keys and holy cards) cost 5c. Summons Mom's foot which will stomp on a random enemy in the current room, dealing 300 damage, If no enemies are in the current room, the foot will target Isaac (and do damage if it hits), however it can be used to break rocks, Gives the player the Whore of Babylon effect for the current room, increasing damage and speed, Teleports the player to the Boss room on the current floor, *, the lost item pool, tarot, card, blue, red, If used in a Super Secret Room containing a Black Heart or Eternal Heart, it will spawn those types of hearts instead, Grants the same effect as 'My Little Unicorn', which makes Isaac invincible and deal 40 contact damage to enemies per hit, Spawns 1 bomb, 1 key, 1 coin, 1 heart, which can be random variants of each, On or below the Womb, this acts as a random teleport, since there are no shops on those floors, Spawns a Slot Machine or a Fortune Machine, Gives the player the Magic Mushroom effect, which increasing size and all stats by 1 for the current room, If you use the Strength card with 12 heart containers, it will take you down to 11 when you leave the room, Gives the player the flying effect for the current room, allowing the player to fly over obstacles in the room, This card is useless if you have any item which allows you to permanently fly, * , the lost item pool, tarot, card, grey, gray, Deals 40 damage to all enemies in the room in a similar style to the Necronomicon, * , the lost item pool, tarot, card, red, blue, Gives the Book of Belial effect for the current room, increasing damage, Spawns some troll bombs at random locations in the current room, Each bomb deals 60 damage (normal bomb damage, On or below the Womb, this acts as a random teleport, since there are no item rooms on those floors, A card with three uses: A full heal, deals 100 damage to all enemies in the current room and reveals the entire map for the current floor (Treasure Map + The Compass), Killing a Devil Beggar, Key Master, or Shell Game Beggar gives you an increased chance of finding Angel rooms instead of Devil rooms. item room pool, red, boom, tnt, * item room, treasure room, item room pool, wooden, cross, brown, Isaac can now hold two trinkets at the same time, Drops a random trinket on the floor when picked up, Allows you to pick up more trinkets while also holding The Tick, * shop room pool, shop item pool, purple, pink, bag, All of Isaac's bombs now leave a poison effect on any enemies within the blast radius, As well as dealing the standard 60 damage for a bomb, it will apply a Damage over Time effect that does 4 or 6 damage per tick, Has a chance to drop from the Super Sloth miniboss fight. This allows you to choose between the item that originally spawned and a HP upgrade every time, This effect applies to most items, including those in the shop and devil room. Gives Isaac a little portal familiar, that moves across the screen as you're firing, The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage, When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. UNLOCK: Unlock this item by getting all hard mode completion marks for the 17 non-tainted characters, Combine with Knife Piece 2 to create a Knife which can be fired across the room, dealing 25 damage to any enemies it comes into contact with, In the Downpour/Dross II, you will find a white flame somewhere, and a room with a mirror in it. red, pink, broken, Better chance to win while gambling at the Shell Game and Fortune Telling Machine, Higher chance to get a random drop after clearing a room, REPENTANCE - Lucky Foot now guarantees positive pill effects, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, treasure room, item room pool, starting, pink, white, yellow, A target is placed on the floor which can be controlled. Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. Heart - 26.6% chance, Trinket - 6.6% chance. with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. However it's not just a really well made mod they added and made adjustments to, there's also yet another path that's added. Related: How to unlock Downpour in Binding of Isaac Repentance. I'm here to provide a little direction as to the best unlocks to go for first. A slow pulsing outline HUD effect appears for cards that would be buffed by Tarot Cloth, To see the full list of Tarot Card effects, check out the Mechanics > Tarot Cloth page, Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect), Tear damage is equal to Isaac's tear damage + 25 flat damage, Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds, Similar to Tammy's Head, this item synergizes with a lot of items (i.e. for example is one of the better ones and beating Greedier with Tainted Isaac wasnt too difficult. longan tree california Of course to unlock them, you need to unlock all of the tainted characters first, and then you can start to focus on the cards. Repentance introduces a whole new mechanic of Red Rooms - extra rooms attached to the current floor. This is decided by whatever you have the least of. Function: Gives Flight, +2 Soul Hearts, Holding down the fire button for 2.35 seconds charges a beam that deals 15 ticks of your tear damage, Unlock Condition: Defeat Mother as Bethany. spray, brown, white, yellow, moms purfume, Tears can now be charged and released in a shotgun style effect, much like Monstro's main attack, Partial charging does nothing - must be fully charged to use, * item room, treasure room, item room pool, pink, body part, monstros lung, On pickup Abaddon converts all your heart containers to black hearts, then gives you +2 more black hearts, Tears now have a chance to induce the fear effect, causing enemies to run away from Isaac for a short period, REPENTANCE - No longer kills Keeper when picked up, just reduces coin health to 1, UNLOCK: Unlock this item by beating the Chest with Azazel, * devil pool, devil room pool, devil deal, red devil sign, abandon, abadon, pentagram, Isaac leaves a trail of tar behind him which will slow down enemies that walk over it, Tears have a chance to slow enemies and their projectiles for a short period of time, The chance to slow enemies can improve based on your luck stat and will always slow enemies at +18 Luck, * item room, treasure room, item room pool, black, grey, gray, The Stop Watch applies a permanent but slight slowing effect to all enemies and their projectiles, The slowing effect has a reduced effect against Brimstone lasers fired by enemies, REPENTANCE - Stop Watch now slows down all enemies in the game once again, but the slow effect is much less drastic. Unlike the regular D6, rerolled items can pick from any item pool, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eden, When used, Isaac dies and becomes The Lost for the current room. Using active items gives a damage up that scales with the charge time, ??? Beat the boss and move on to Corpse II to finally take on Mother. I just unlocked the Holy Brimstone and hopefully that will give more wiggle room for other unlocks. Unlocked from the 'Dedication' achievement (participate in 31 dailies in a row), I'm Drowsy - Slows all enemies for the rest of the current room, I'm excited!!! Holding down the fire button again will quickly release all stored teared, The charge time and max tears stored scales with your current tears stat, Greatly reduce Isaac's size, to an extent where some enemy tears will now travel straight over him without dealing damage if they are high off the ground. a bomb can become a troll bomb, or a dropped coin can become a dime, UNLOCK: Unlock this trinket by defeating Isaac, ?? The item grants Isaac a fly follower that protects him from all enemy bullets, and it does that job almost too well. When the charge bar gets to zero it will grant you a brief period of invincibility, If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage, During the invincibility period, Isaac deals 3.5 contact damage to enemies and beams of light will strike down from the sky, dealing 15 damage, If damage is blocked perfectly at the exact second the charge bar reaches zero, it will release holy beams in four directions and grant a brief shile effect, The invincibility effect is shown via a rapid flashing animation, * angel room pool, god room pool, angel room item, white, blue, ball, circle, After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds, Allows you to open the door at the beginning of Depths II that leads to the Mausoluem, When unlocked, is guaranteed to drop after the Mom's Foot boss fight, The Polaroid will always spawn on the left pedestal, UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times, After taking damage, if you have half a red heart or less, The Negative will deal 40 damage to all enemies in the room, The Negative will always spawn on the right pedestal, UNLOCK: Unlock this item by beating Satan in Sheol 5 times, * mom's foot, mom fight, mom boss, dark room, photo, family, kodak, inverted, You no longer shoot tears and instead now control a single large tear with the arrow keys, Items which increase your tears stat will cause the tear to deal damage at a faster rate, Items which increase your shot speed cause the tear to travel faster across the screen, Ludo and Brimstone create a large controllable red ring of death that does massive damage to anything in its path, Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage, * item room, treasure room, item room pool, eye, pink, grey, gray, robot, REPENTANCE - Soy Milk tears now cause drastically less knockback, * item room, treasure room, item room pool, white, glass, square, Isaac's tears become homing and have an aura around them, which will deal a flat 2 damage per tick to anything inside its radius, Multiple GodHeads doesn't stack the aura damage, UNLOCK: Unlock this item by completing all post-it note marks in hard mode with The Lost character, * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye, Gives Isaac an extra life on death, exactly the same as Lazarus' default respawn effect, When you die with this item, you respawn in the same room with 1 heart and the Anemic item, The game considers you to be a different character (Lazarus II) when this effect activates, UNLOCK: Unlock this item by beating the Isaac boss with Lazarus, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Lost & # x27 ; s post-it on Hard to unlock Downpour In of... 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